{"product_id":"pde3a-polyclonal-antibody-bt-ap12871","title":"PDE3A Polyclonal Antibody - BT-AP12871","description":"\u003cp\u003ePDE3A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12871-20, BT-AP12871-50, BT-AP12871-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PDE3A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: cGMP-inhibited 3',5'-cyclic phosphodiesterase A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14432; Mouse: Q9Z0X4; Rat: Q62865\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: cGMP-inhibited 3',5'-cyclic phosphodiesterase A;EC 3.1.4.17;Cyclic GMP-inhibited phosphodiesterase A;CGI-PDE A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5139\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239282204851,"sku":"BT-AP12871-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239282237619,"sku":"BT-AP12871-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239282270387,"sku":"BT-AP12871-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dbfc404d-ee04-4088-b069-b87fec0c251b.png?v=1769392481","url":"https:\/\/afsbio.com\/products\/pde3a-polyclonal-antibody-bt-ap12871","provider":"AFSBio Inc.","version":"1.0","type":"link"}