{"product_id":"pde4b-c-d-phospho-ser133-119-190-polyclonal-antibody-ra28604","title":"PDE4B\/C\/D (phospho Ser133\/119\/190) Polyclonal Antibody - RA28604","description":"\u003cp\u003ePDE4B\/C\/D (phospho Ser133\/119\/190) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28604-50, RA28604-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: phosphodiesterase 4B (PDE4B) Homo sapiens This gene is a member of the type IV, cyclic AMP (cAMP) -specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: PDE4B; DPDE4; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5144\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 76\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q07343\/Q08493\/Q08499\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122354512051,"sku":"RA28604-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122354544819,"sku":"RA28604-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_07dfb894-c0a3-4ee8-ac1a-6a2cf89cb2ba.png?v=1773347928","url":"https:\/\/afsbio.com\/products\/pde4b-c-d-phospho-ser133-119-190-polyclonal-antibody-ra28604","provider":"AFSBio Inc.","version":"1.0","type":"link"}