{"product_id":"pde4c-polyclonal-antibody-e-ab-90559","title":"PDE4C Polyclonal Antibody - E-AB-90559","description":"\u003cp\u003ePDE4C Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90559-60, E-AB-90559-120, E-AB-90559-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PDE4C\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PDE4C; DPDE1; PDE21\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q08493\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PDE4C\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:400\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 67kDa\/75kDa\/79kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43144011317427,"sku":"E-AB-90559-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43144011350195,"sku":"E-AB-90559-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43144011382963,"sku":"E-AB-90559-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_69a610ea-9963-41d7-9838-127af59bc760.png?v=1710245218","url":"https:\/\/afsbio.com\/products\/pde4c-polyclonal-antibody-e-ab-90559","provider":"AFSBio Inc.","version":"1.0","type":"link"}