{"product_id":"pde5a-polyclonal-antibody-bt-ap12876","title":"PDE5A Polyclonal Antibody - BT-AP12876","description":"\u003cp\u003ePDE5A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12876-20, BT-AP12876-50, BT-AP12876-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5andapos;-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PDE5A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: cGMP-specific 3',5'-cyclic phosphodiesterase\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O76074; Mouse: Q8CG03; Rat: O54735\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: cGMP-specific 3',5'-cyclic phosphodiesterase;EC 3.1.4.35;cGMP-binding cGMP-specific phosphodiesterase;CGB-PDE\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8654\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239282401459,"sku":"BT-AP12876-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239282434227,"sku":"BT-AP12876-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239282466995,"sku":"BT-AP12876-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_10120181-63b6-40df-bca0-940185036109.png?v=1769392484","url":"https:\/\/afsbio.com\/products\/pde5a-polyclonal-antibody-bt-ap12876","provider":"AFSBio Inc.","version":"1.0","type":"link"}