{"product_id":"pdgfralpha-mouse-monoclonal-antibody-4g11-bt-mca1010","title":"PDGFRAlpha mouse Monoclonal Antibody (4G11) - BT-MCA1010","description":"\u003cp\u003ePDGFRAlpha mouse Monoclonal Antibody (4G11)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA1010-20, BT-MCA1010-50, BT-MCA1010-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PDGFRA\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Rat,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PDGFRA\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P16234; Mouse: P26618; Rat: P20786\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PDGFRA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5156\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240045469875,"sku":"BT-MCA1010-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240045502643,"sku":"BT-MCA1010-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240045535411,"sku":"BT-MCA1010-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0fc6b64c-86a8-4b22-abad-04d256c909ca.png?v=1769402626","url":"https:\/\/afsbio.com\/products\/pdgfralpha-mouse-monoclonal-antibody-4g11-bt-mca1010","provider":"AFSBio Inc.","version":"1.0","type":"link"}