{"product_id":"pdgfralpha-polyclonal-antibody-bt-ap12881","title":"PDGFRAlpha Polyclonal Antibody - BT-AP12881","description":"\u003cp\u003ePDGFRAlpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12881-20, BT-AP12881-50, BT-AP12881-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Signal transduction; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PDGFRA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Platelet-derived growth factor receptor alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P16234; Mouse: P26618; Rat: P20786\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Platelet-derived growth factor receptor alpha;PDGF-R-alpha;PDGFR-alpha;EC 2.7.10.1;Alpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD140 ant; Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; EC 2.7.10.1; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; PDGFR-2; CD antigen CD140a\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5156; Mouse: 18595; Rat: 25267\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239282696371,"sku":"BT-AP12881-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239282729139,"sku":"BT-AP12881-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239282761907,"sku":"BT-AP12881-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8e6be435-e5ed-4465-b22f-9275e3d51aa0.png?v=1769392488","url":"https:\/\/afsbio.com\/products\/pdgfralpha-polyclonal-antibody-bt-ap12881","provider":"AFSBio Inc.","version":"1.0","type":"link"}