{"product_id":"pdk1-phospho-tyr243-rabbit-pab-es20214","title":"PDK1 (Phospho Tyr243) rabbit pAb - ES20214","description":"\u003cp\u003ePDK1 (Phospho Tyr243) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20214-50, ES20214-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation\/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (EC 2.7.11.2; Pyruvate dehydrogenase kinase isoform 1)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human PDHK1 (Phospho Tyr243)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 50kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5163\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q15118\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Mitochondrion matrix.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202429509811,"sku":"ES20214-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202429542579,"sku":"ES20214-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_573d11e8-94e4-4d25-8f13-337612618ade.png?v=1767129029","url":"https:\/\/afsbio.com\/products\/pdk1-phospho-tyr243-rabbit-pab-es20214","provider":"AFSBio Inc.","version":"1.0","type":"link"}