{"product_id":"pdk1-polyclonal-antibody-bt-ap07028","title":"PDK1 Polyclonal Antibody - BT-AP07028","description":"\u003cp\u003ePDK1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07028-20, BT-AP07028-50, BT-AP07028-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation\/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for PDK1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PDPK1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PDK1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 49244\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q15118; Mouse: Q8BFP9; Rat: Q63065\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5163; Mouse: 228026\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239822090419,"sku":"BT-AP07028-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239822123187,"sku":"BT-AP07028-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239822155955,"sku":"BT-AP07028-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_28dfc97c-a0bf-495a-82b6-ffdfe049c7d7.png?v=1769399614","url":"https:\/\/afsbio.com\/products\/pdk1-polyclonal-antibody-bt-ap07028","provider":"AFSBio Inc.","version":"1.0","type":"link"}