{"product_id":"pdx1-monoclonal-antibody-bt-mca2456","title":"PDX1 Monoclonal Antibody - BT-MCA2456","description":"\u003cp\u003ePDX1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2456-50, BT-MCA2456-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PDX1\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2G12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PDX1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PDX1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 30.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P52945\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3651\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238587982003,"sku":"BT-MCA2456-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238588014771,"sku":"BT-MCA2456-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b25f4642-b108-4b9d-af12-01fa0df4e019.png?v=1769382842","url":"https:\/\/afsbio.com\/products\/pdx1-monoclonal-antibody-bt-mca2456","provider":"AFSBio Inc.","version":"1.0","type":"link"}