{"product_id":"pe-anti-mouse-rat-foxp3-antibody-fjk-16s-pe-30055u","title":"PE Anti-Mouse\/Rat Foxp3 Antibody (FJK-16s) - PE-30055U","description":"PE Anti-Mouse\/Rat Foxp3 Antibody (FJK-16s)\n\nSizes: 25μg, 100μg\n\nCatalogue Numbers: PE-30055U-25, PE-30055U-100\n\nCitations, Manuals and MSDS Available upon request.\n\nTarget: Mouse\/Rat Foxp3\n\nForm: Liquid\n\nConjugation: PE\n\nConjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585\/42 nm bandpass filter).\n\n \n\n \n\nRat\n\nHost: Rat\n\nClonality: Monoclonal\n\nClone ID: FJK-16s\n\nIsotype: IgG2a, κ\n\nStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\n\nBackground: FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4\u003csup\u003e+\u003c\/sup\u003e\/CD25\u003csup\u003e-\u003c\/sup\u003e cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in \"scurfy\" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.\n\n \n\nSynonyms: IPEXJM2ScurfinZinc finger protein JM2| Forkhead box protein P3\n\n \n\nUniprot ID: Q99JB6\n\nReactivity: Mouse\/Rat\n\nTested Application: FC\n\nRecommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg\/10⁶ cells in 100 μL volume].\n\nGene ID: 20371\n\n \n\n \n\nCategory: Flow cytometryometry Antibodies\n\nResearch Use Only","brand":"Fine Biotech","offers":[{"title":"25μg","offer_id":45346371764403,"sku":"PE-30055U-25","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":45346371797171,"sku":"PE-30055U-100","price":938.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/pe-anti-mouse-rat-foxp3-antibody-fjk-16s-pe-30055u","provider":"AFSBio Inc.","version":"1.0","type":"link"}