{"product_id":"pe-cf594-rabbit-anti-human-bcl6-monoclonal-antibody-a27730","title":"PE-CF594 Rabbit anti-Human BCL6 Monoclonal Antibody - A27730","description":"\u003cp\u003ePE-CF594 Rabbit anti-Human BCL6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A27730-100, A27730-200, A27730-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC (intra)\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 79kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 604\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P41182\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: BCL5; LAZ3; BCL6A; ZNF51; ZBTB27\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, B Cell Receptor Signaling Pathway\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: BCL6\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: PE-CF594. Ex:566nm. Em:615nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC57886\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189331321011,"sku":"A27730-100","price":417.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189331353779,"sku":"A27730-200","price":711.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189331386547,"sku":"A27730-500","price":1313.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_d4e050ad-2035-4bf9-b1c4-f21dd5e22a79.png?v=1766421589","url":"https:\/\/afsbio.com\/products\/pe-cf594-rabbit-anti-human-bcl6-monoclonal-antibody-a27730","provider":"AFSBio Inc.","version":"1.0","type":"link"}