{"product_id":"pe-elab-fluor®-594-anti-mouse-cd45-antibody-30-f11-e-ab-f1136up","title":"PE\/Elab Fluor® 594 Anti-Mouse CD45 Antibody [30-F11] - E-AB-F1136UP","description":"\u003cp\u003ePE\/Elab Fluor® 594 Anti-Mouse CD45 Antibody [30-F11]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1136UP-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD45\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: PE\/Elab Fluor® 594\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg\/10^6 cells in 100 μL volume].\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG2b, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 30-F11\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P06800\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09843P\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 19264\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43157409530035,"sku":"E-AB-F1136UP-100","price":266.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e5019b2b-89f1-4296-b5f8-6544ecfbb7b3.png?v=1710514354","url":"https:\/\/afsbio.com\/products\/pe-elab-fluor%c2%ae-594-anti-mouse-cd45-antibody-30-f11-e-ab-f1136up","provider":"AFSBio Inc.","version":"1.0","type":"link"}