{"product_id":"pe-rabbit-anti-human-cd220-monoclonal-antibody-a28239","title":"PE Rabbit anti-Human CD220 Monoclonal Antibody - A28239","description":"\u003cp\u003ePE Rabbit anti-Human CD220 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A28239-100, A28239-200, A28239-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 156 kDa\u003cbr\u003e\n  \u003cbr\u003e\nSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3643\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P06213\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HHF5; CD220\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Protein phosphorylation, Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, AMPK Signaling Pathway, Insulin Receptor Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Immunology Inflammation, CDs, Neuroscience, Cardiovascular, Heart, Cardiovascular diseases, Heart disease\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: INSR\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: PE. Ex:565nm. Em:574nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC77158\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189323686067,"sku":"A28239-100","price":305.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189323718835,"sku":"A28239-200","price":529.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189323751603,"sku":"A28239-500","price":1187.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5c112001-47bf-4926-93a0-02557437e1e3.png?v=1766421456","url":"https:\/\/afsbio.com\/products\/pe-rabbit-anti-human-cd220-monoclonal-antibody-a28239","provider":"AFSBio Inc.","version":"1.0","type":"link"}