{"product_id":"pe-rabbit-anti-human-phospho-histone-h2ax-s139-monoclonal-antibody-ap1529","title":"PE Rabbit anti-Human Phospho-Histone H2AX-S139 Monoclonal Antibody - AP1529","description":"\u003cp\u003ePE Rabbit anti-Human Phospho-Histone H2AX-S139 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: AP1529-100, AP1529-200, AP1529-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Phosphorylated Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC (intra)\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 15kDa Immunogen: Synthetic peptide.\u003c\/p\u003e \n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3014\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P16104\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: H2A.X; H2A\/X; H2AFX\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Protein phosphorylation, ATM Signaling Pathway\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: H2AX\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: PE. Ex:565nm. Em:574nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC70320\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189341413555,"sku":"AP1529-100","price":403.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189341446323,"sku":"AP1529-200","price":683.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189341479091,"sku":"AP1529-500","price":1271.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_72d9735c-97c8-487f-a5d0-adf7f40b6aa9.png?v=1766421753","url":"https:\/\/afsbio.com\/products\/pe-rabbit-anti-human-phospho-histone-h2ax-s139-monoclonal-antibody-ap1529","provider":"AFSBio Inc.","version":"1.0","type":"link"}