{"product_id":"per1-polyclonal-antibody-e-ab-62160","title":"PER1 Polyclonal Antibody - E-AB-62160","description":"\u003cp\u003ePER1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62160-60, E-AB-62160-120, E-AB-62160-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PER1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PER1; PER; RIGUI; hPER\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O15534\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK\/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER\/CRY heterodimers to interact with CLOCK\/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PER1 (NP_002607.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC \t1:50-1:100   IF \t1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136861896883,"sku":"E-AB-62160-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136861929651,"sku":"E-AB-62160-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136861962419,"sku":"E-AB-62160-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_478a9bdb-56c8-4af7-a8c9-c9ab88f880ac.png?v=1709992914","url":"https:\/\/afsbio.com\/products\/per1-polyclonal-antibody-e-ab-62160","provider":"AFSBio Inc.","version":"1.0","type":"link"}