{"product_id":"percp-anti-mouse-cd45r-b220-antibody-ra3-3a-1-6-1-pcp-30299u","title":"PerCP Anti-Mouse CD45R\/B220 Antibody (RA3.3A 1\/6.1) - PCP-30299U","description":"PerCP Anti-Mouse CD45R\/B220 Antibody (RA3.3A 1\/6.1)\n\nSizes: 25μg, 100μg\n\nCatalogue Numbers: PCP-30299U-25, PCP-30299U-100\n\nCitations, Manuals and MSDS Available upon request.\n\nTarget: Mouse CD45R\/B220\n\nForm: Liquid\n\nConjugation: PerCP\n\nConjugation Information: PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690\/50 nm bandpass filter).\n\n \n\n \n\nRat\n\nHost: Rat\n\nClonality: Monoclonal\n\nClone ID: RA3.3A 1\/6.1\n\nIsotype: IgM, κ\n\nStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\n\nBackground: CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas\u003csup\u003elpr\u003c\/sup\u003e and MRL-Fas\u003csup\u003egld\u003c\/sup\u003e mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.\n\n \n\nSynonyms: B220\n\n \n\n \n\nReactivity: Mouse\n\nTested Application: FC\n\nRecommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg\/10⁶ cells in 100 μL volume].\n\nGene ID: 19264, 5788\n\n \n\n \n\nCategory: Flow cytometryometry Antibodies\n\nResearch Use Only","brand":"Fine Biotech","offers":[{"title":"25μg","offer_id":45346387329203,"sku":"PCP-30299U-25","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":45346387361971,"sku":"PCP-30299U-100","price":686.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/percp-anti-mouse-cd45r-b220-antibody-ra3-3a-1-6-1-pcp-30299u","provider":"AFSBio Inc.","version":"1.0","type":"link"}