{"product_id":"pex2-polyclonal-antibody-bs3900","title":"PEX2 Polyclonal Antibody-BS3900","description":"\u003cp\u003ePEX2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3900-50, BS3900-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P28328\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Peroxisomes are involved in numerous catabolic and anabolic pathways, including β-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. Peroxins are proteins involved in peroxisome biogenesis. The peroxisome biogenesis factor Peroxin 2 (also designated Pex2) is an integral membrane protein of peroxisomes. Defects in the PXMP3 gene encoding Peroxin 2 are the cause of Zellweger syndrome-1 (ZWS-1), an autosomal recessive disorder due to defective import mechanisms for peroxisomal matrix enzymes. ZWS-1 is a severe form of the peroxisome-biogenesis disorders, a group of genetically heterogeneous, lethal diseases that are characterized by neuronal, hepatic and renal abnormalities, mental retardation and, in their most severe form,death within the first year of life.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PEX2 polyclonal antibody detects endogenous levels of PEX2 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of PEX2 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane1:A549 whole cell lysate(40ug)\u003cbr\u003e\nLane2:A2780 whole cell lysate(40ug)\u003cbr\u003e\nLane3:3T3-L1 whole cell lysate(40ug)\u003cbr\u003e\nLane4:The kidney tube tissue lysate of mouse(40ug)\u003cbr\u003e\nLane5:The lung tube tissue lysate of rat(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~34kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Peroxisome biogenesis factor 2; 35 kDa peroxisomal membrane protein; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1; PAF-1; RING finger protein 72; PEX2; PAF1; PMP3; PMP35; PXMP3; RNF72\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human PEX2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908773286067,"sku":"BS3900-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908773318835,"sku":"BS3900-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c2d8bf5e-83f9-42db-8f98-295a8916782e.jpg?v=1703006900","url":"https:\/\/afsbio.com\/products\/pex2-polyclonal-antibody-bs3900","provider":"AFSBio Inc.","version":"1.0","type":"link"}