{"product_id":"pfk-2-car-phospho-ser483-polyclonal-antibody-ra28701","title":"PFK-2 car (phospho Ser483) Polyclonal Antibody - RA28701","description":"\u003cp\u003ePFK-2 car (phospho Ser483) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28701-50, RA28701-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: 6-phosphofructo-2-kinase\/fructose-2,6-biphosphatase 2 (PFKFB2) Homo sapiens The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: PFKFB2; 6-phosphofructo-2-kinase\/fructose-2; 6-bisphosphatase 2; 6PF-2-K\/Fru-2,6-P2ase 2; PFK\/FBPase 2; 6PF-2-K\/Fru-2,6-P2ase heart-type isozyme\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5208\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 58\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O60825\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122359656627,"sku":"RA28701-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122359689395,"sku":"RA28701-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_90e9c166-aca4-42f6-b164-60f89f952dee.png?v=1773347984","url":"https:\/\/afsbio.com\/products\/pfk-2-car-phospho-ser483-polyclonal-antibody-ra28701","provider":"AFSBio Inc.","version":"1.0","type":"link"}