{"product_id":"pfk-2-liv-rabbit-pab-es3183","title":"PFK-2 liv rabbit pAb - ES3183","description":"\u003cp\u003ePFK-2 liv rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3183-50, ES3183-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2, 6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2, 6-biphosphate using independent catalytic domains. Fructose-2, 6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2, 6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase\/fructose-2; 6-bisphosphatase 1; 6PF-2-K\/Fru-2, 6-P2ase 1; PFK\/FBPase 1; 6PF-2-K\/Fru-2, 6-P2ase liver isozyme\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PFKFB1. AA range:406-455\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 58kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5207\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P16118\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: cytosol, 6-phosphofructo-2-kinase\/fructose-2, 6-biphosphatase complex,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202120212659,"sku":"ES3183-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202120245427,"sku":"ES3183-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_91c95c6a-dc02-4a4c-903e-9bd49992ddb3.png?v=1767122375","url":"https:\/\/afsbio.com\/products\/pfk-2-liv-rabbit-pab-es3183","provider":"AFSBio Inc.","version":"1.0","type":"link"}