{"product_id":"pfk-2-liv-tes-polyclonal-antibody-bt-ap07091","title":"PFK-2 liv\/tes Polyclonal Antibody - BT-AP07091","description":"\u003cp\u003ePFK-2 liv\/tes Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07091-20, BT-AP07091-50, BT-AP07091-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of 6-phosphofructo-2-kinase\/fructose-2,6-biphosphatase 1 is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for PFKFB1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PFKFB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PFK-2 liv\/tes Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 54681\/54040\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P16118\/Q16877; Rat: P07953\/P25114\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase\/fructose-2; 6-bisphosphatase 1; 6PF-2-K\/Fru-2,6-P2ase 1; PFK\/FBPase 1; 6PF-2-K\/Fru-2,6-P2ase liver isozyme; PFKFB4; 6-phosphofructo-2-kinase\/fructose-2,6-b\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5207\/5210; Mouse: 18639\/270198; Rat: 24638\/54283\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239828283571,"sku":"BT-AP07091-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239828316339,"sku":"BT-AP07091-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239828349107,"sku":"BT-AP07091-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5fe0218b-b451-4782-a1d3-9005d36f28ca.png?v=1769399685","url":"https:\/\/afsbio.com\/products\/pfk-2-liv-tes-polyclonal-antibody-bt-ap07091","provider":"AFSBio Inc.","version":"1.0","type":"link"}