{"product_id":"pfk-2-liv-tes-polyclonal-antibody-ra28705","title":"PFK-2 liv\/tes Polyclonal Antibody - RA28705","description":"\u003cp\u003ePFK-2 liv\/tes Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28705-50, RA28705-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: 6-phosphofructo-2-kinase\/fructose-2,6-biphosphatase 1 (PFKFB1) Homo sapiens This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase\/fructose-2; 6-bisphosphatase 1; 6PF-2-K\/Fru-2,6-P2ase 1; PFK\/FBPase 1; 6PF-2-K\/Fru-2,6-P2ase liver isozyme; PFKFB4; 6-phosphofructo-2-kinase\/fructose-2,6-bisphosphatase 4; 6PF-2-K\/Fru-2,6-P2ase 4;\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5207\/5210\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 54\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P16118\/Q16877\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122359918771,"sku":"RA28705-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122359951539,"sku":"RA28705-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_da5ab8b9-313d-4d7b-ad9d-dd85dde85942.png?v=1773347987","url":"https:\/\/afsbio.com\/products\/pfk-2-liv-tes-polyclonal-antibody-ra28705","provider":"AFSBio Inc.","version":"1.0","type":"link"}