{"product_id":"pfkfb2-y14-polyclonal-antibody-bs2458","title":"PFKFB2 (Y14) Polyclonal Antibody - BS2458","description":"\u003cp\u003ePFKFB2 (Y14) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2458-50, BS2458-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2, 6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regμlator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2, 6-bisphosphate, and contains fructose-2, 6-biphosphatase activity that catalyzes the degradation of fructose-2, 6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PFK-2 car, PFK-2 cardiac, 6-phosphofructo-2-kinase\/fructose-2, 6-bisphosphatase 2, 6PF-2-K\/Fru-2, 6-P2ase 2, PFK\/FBPase 2, 6PF-2-K\/Fru-2, 6-P2ase heart-type isozyme, 6-phosphofructo-2-kinase, Fructose-2, 6-bisphosphatase, PFKFB2\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 1-50 of Human PFKFB2.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PFKFB2 (Y14) polyclonal antibody detects endogenous levels of PFKFB2 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 58 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Warburg Effect, Glutamine Metabolism,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: O60825\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946244497587,"sku":"BS2458-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946244530355,"sku":"BS2458-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/pfkfb2-y14-polyclonal-antibody-bs2458","provider":"AFSBio Inc.","version":"1.0","type":"link"}