{"product_id":"pfkl-e724-polyclonal-antibody-bs1943","title":"PFKL (E724) Polyclonal Antibody-BS1943","description":"\u003cp\u003ePFKL (E724) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1943-50, BS1943-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P17858\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate in glycolysis. There are three isozymes: muscle-type, liver-type, and platelet-type. The liver-type PFK (PFKL) is the predominant subunit of PFK found in the liver. Research studies have shown that because of its location on chromosome 21, this enzyme is overexpressed in Down Syndrome\/trisomy 21. PFKL also may have a role in the physiological response to a low fat diet.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry (IHC) analyzes of PFKL (E724) pAb in paraffin-embedded human brain tissue.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 85 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PFKL (E724) polyclonal antibody detects endogenous levels of PFKL protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: 6-phosphofructokinase; liver type; Phosphofructokinase 1; Phosphohexokinase; Phosphofructo-1-kinase isozyme B; PFK-B;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 700-750 of Human PFKL.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939281309875,"sku":"BS1943-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939281342643,"sku":"BS1943-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_68e1026e-99b8-4b5f-9b37-95820b0bed1e.jpg?v=1704545764","url":"https:\/\/afsbio.com\/products\/pfkl-e724-polyclonal-antibody-bs1943","provider":"AFSBio Inc.","version":"1.0","type":"link"}