{"product_id":"pgam1-polyclonal-antibody-bs91061","title":"PGAM1 Polyclonal Antibody-BS91061","description":"\u003cp\u003ePGAM1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS91061-50, BS91061-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P18669(Human) Q9DBJ1(Mouse) P25113(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:2,000\u003cbr\u003e\nIHC:1:50-1:100\u003cbr\u003e\nFC:1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Members of the PGAM (phosphoglycerate mutase) family of proteins are important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism. They are responsible for catalyzing the transfer of phospho groups between the carbon atoms of phosphoglycerates. In mammals there are two types of PGAM isozymes: PGAM1 (also known as PGAMB) and PGAM2 (also known as PGAMA). In the cell, PGAM1 and PGAM2 exist as either homodimers or heterodimers and are responsible for the interconversion of 3-phosphoglycerate and 2-phosphoglycerate. PGAM2 homodimers are expressed in skeletal muscle, mature sperm cells and heart; PGAM1 homodimers are found in most other tissues; and PGAM1\/PGAM2 heterodimers are found exclusively in the heart. PGAM4, also known as PGAM3, is a protein formerly considered to be specific to humans. Initially the PGAM4 gene was described as a pseudogene but it is now known to encode a functional protein at least 25 million years old. The gene encoding PGAM4 is believed to have originated by retrotransposition, with the original copy being the PGAM1 gene.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PGAM1 polyclonal antibody detects endogenous levels of PGAM1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of PGAM1 on different lysates using anti-PGAM1 antibody at 1\/2,000 dilution.\u003cbr\u003e\n Positive control:\u003cbr\u003e\n Lane 1: A431 \u003cbr\u003e\n Lane 2: A549\u003cbr\u003e\n Lane 3: Rat brain \u003cbr\u003e\n Lane 4: Mouse brain, Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-PGAM1 antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: PGAM-B, PGAM1, PGAMA, BPG dependent PGAM 1, BPG dependent PGAM1, BPG-dependent PGAM 1, OTTHUMP00000059414, PGAM 1, PGAM A, PGAM B, PGAM-B, PGAM1, PGAM1, PGAMA, PGAMB, Phosphoglycerate mutase 1, Phosphoglycerate mutase 1 brain, Phosphoglycerate mutase A, Phosphoglycerate mutase A nonmuscle form, Phosphoglycerate mutase isozyme B,\u003c\/p\u003e \n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42984612266163,"sku":"BS91061-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42984612298931,"sku":"BS91061-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cc7c402e-6a53-499e-a9c8-859f96ffe4bc.jpg?v=1705919322","url":"https:\/\/afsbio.com\/products\/pgam1-polyclonal-antibody-bs91061","provider":"AFSBio Inc.","version":"1.0","type":"link"}