{"product_id":"pgc-1alpha-monoclonal-antibody-bt-mca4827","title":"PGC-1alpha Monoclonal Antibody - BT-MCA4827","description":"\u003cp\u003ePGC-1alpha Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4827-50, BT-MCA4827-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PGC-1alpha\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1G8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PGC-1alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PGC-1alpha expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 91kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9UBK2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PPARGC1A, LEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1(alpha)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10891\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238424895667,"sku":"BT-MCA4827-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238424928435,"sku":"BT-MCA4827-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ab98e7fa-ea06-42d9-a8af-0e6fbdf39b5d.png?v=1769380577","url":"https:\/\/afsbio.com\/products\/pgc-1alpha-monoclonal-antibody-bt-mca4827","provider":"AFSBio Inc.","version":"1.0","type":"link"}