{"product_id":"pgd-rabbit-polyclonal-antibody-es6578","title":"PGD Rabbit Polyclonal Antibody - ES6578","description":"\u003cp\u003ePGD Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6578-50, ES6578-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PGD, PGDH, 6-phosphogluconate dehydrogenase, decarboxylating\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PGD. AA range:71-120\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: PGD\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PGD Polyclonal Antibody detects endogenous levels of PGD protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p: 100-300.Western Blot: 1\/500 - 1\/2000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Heart, Lung,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 40kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Pentose phosphate pathway, Glutathione metabolism, Metabolic pathways, Carbon metabolism\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: 6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH\u003cbr\u003e\nPathway: Carbohydrate degradation, pentose phosphate pathway, D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3\/3\u003cbr\u003e\nSimilarity: Belongs to the 6-phosphogluconate dehydrogenase family\u003cbr\u003e\nSubunit: Homodimer\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: PGD\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: 6-phosphogluconate dehydrogenase decarboxylating\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 110208\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q9DCD0\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 1.0036e+008\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P85968\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46313615818931,"sku":"ES6578-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46313615851699,"sku":"ES6578-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/pgd-rabbit-polyclonal-antibody-es6578","provider":"AFSBio Inc.","version":"1.0","type":"link"}