{"product_id":"phapi2-rabbit-polyclonal-antibody-es4504","title":"PHAPI2 Rabbit Polyclonal Antibody - ES4504","description":"\u003cp\u003ePHAPI2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4504-50, ES4504-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ANP32B, APRIL, PHAPI2, Acidic leucine-rich nuclear phosphoprotein 32 family member B, Acidic protein rich in leucines, Putative HLA-DR-associated protein I-2, PHAPI2, Silver-stainable protein SSP29\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: PHAPI2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PHAPI2 Polyclonal Antibody detects endogenous levels of PHAPI2 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 29kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity\u003cbr\u003e\nSimilarity: Belongs to the ANP32 family\u003cbr\u003e\nSimilarity: Contains 4 LRR (leucine-rich) repeats\u003cbr\u003e\nSubcellular Location: Accumulates in the nuclei at the S phase\u003cbr\u003e\nTissue Specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: [Isoform 1]: Nucleus Cytoplasm Accumulates in the nuclei at the S phase, [Isoform 2]: Cytoplasm Lacks a nuclear localization signal\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ANP32B\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member B\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 67628\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q9EST5\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 170724\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q9EST6\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46316594725043,"sku":"ES4504-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46316594757811,"sku":"ES4504-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/phapi2-rabbit-polyclonal-antibody-es4504","provider":"AFSBio Inc.","version":"1.0","type":"link"}