{"product_id":"phb-monoclonal-antibody-bt-mca3263","title":"PHB Monoclonal Antibody - BT-MCA3263","description":"\u003cp\u003ePHB Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3263-50, BT-MCA3263-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling, Cell biology, Cancer, Metabolism, Tags and, cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PHB\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5H7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PHB\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PHB expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 30kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P35232\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PHB1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5245\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238590668979,"sku":"BT-MCA3263-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238590701747,"sku":"BT-MCA3263-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4fecdc20-1bc3-401c-8982-80bc15948dc0.png?v=1769382863","url":"https:\/\/afsbio.com\/products\/phb-monoclonal-antibody-bt-mca3263","provider":"AFSBio Inc.","version":"1.0","type":"link"}