{"product_id":"phlp1-polyclonal-antibody-bt-ap12999","title":"PHLP1 Polyclonal Antibody - BT-AP12999","description":"\u003cp\u003ePHLP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12999-20, BT-AP12999-50, BT-AP12999-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the serine\/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine\/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PHLPP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PH domain leucine-rich repeat-containing protein phosphatase 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60346; Mouse: Q8CHE4; Rat: Q9WTR8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PH domain leucine-rich repeat-containing protein phosphatase 1;EC 3.1.3.16;Pleckstrin homology domain-containing family E member 1;PH domain-containing family E member 1;Suprachiasmatic nucleus\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23239\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239285842099,"sku":"BT-AP12999-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239285874867,"sku":"BT-AP12999-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239285907635,"sku":"BT-AP12999-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b959ef7a-bb5b-416b-8886-542e93f0084c.png?v=1769392537","url":"https:\/\/afsbio.com\/products\/phlp1-polyclonal-antibody-bt-ap12999","provider":"AFSBio Inc.","version":"1.0","type":"link"}