{"product_id":"phospho-4e-bp1-thr70-polyclonal-antibody-bz16310","title":"Phospho-4E BP1 (Thr70) Polyclonal Antibody-BZ16310","description":"\u003cp\u003ePhospho-4E BP1 (Thr70) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16310-50, BZ16310-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q13541\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC: 1\/50-1\/100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase\/Akt pathway and FRAP\/mTOR kinase regulate 4E-BP1 activity.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue using Phospho-4E BP1 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval. Sample withBlocking peptide on the right.\u003c\/p\u003e\n\n \n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human EIF4EBP1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42932542734515,"sku":"BZ16310-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42932542767283,"sku":"BZ16310-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_9259782f-1acc-47dd-ba35-62d0efe2c117.jpg?v=1704284759","url":"https:\/\/afsbio.com\/products\/phospho-4e-bp1-thr70-polyclonal-antibody-bz16310","provider":"AFSBio Inc.","version":"1.0","type":"link"}