{"product_id":"phospho-accalpha-s80-polyclonal-antibody-bt-phs00595","title":"Phospho-ACCAlpha (S80) Polyclonal Antibody - BT-PHS00595","description":"\u003cp\u003ePhospho-ACCAlpha (S80) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00595-20, BT-PHS00595-50, BT-PHS00595-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation\/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for ACACA.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACACA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-ACCalpha (S80) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 265554\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13085; Mouse: Q5SWU9; Rat: P11497\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACACA; ACAC; ACC1; ACCA; Acetyl-CoA carboxylase 1; ACC1; ACC-alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 31; Mouse: 107476; Rat: 60581\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240013619379,"sku":"BT-PHS00595-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240013652147,"sku":"BT-PHS00595-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240013684915,"sku":"BT-PHS00595-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_db27da02-8097-4b86-996d-211798cd4ff7.png?v=1769402131","url":"https:\/\/afsbio.com\/products\/phospho-accalpha-s80-polyclonal-antibody-bt-phs00595","provider":"AFSBio Inc.","version":"1.0","type":"link"}