{"product_id":"phospho-adducinalpha-t445-polyclonal-antibody-bt-phs00955","title":"Phospho-AdducinAlpha (T445) Polyclonal Antibody - BT-PHS00955","description":"\u003cp\u003ePhospho-AdducinAlpha (T445) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00955-20, BT-PHS00955-50, BT-PHS00955-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)\/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags and Cell Markers; Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ADD1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-Adducin alpha (T445) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80955\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35611; Mouse: Q9QYC0; Rat: Q63028\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ADD1; ADDA; Alpha-adducin; Erythrocyte adducin subunit alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 118; Mouse: 11518; Rat: 24170\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240020435123,"sku":"BT-PHS00955-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240020467891,"sku":"BT-PHS00955-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240020500659,"sku":"BT-PHS00955-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ac88fb77-2751-41b2-86b4-eb2da1c5ebca.png?v=1769402237","url":"https:\/\/afsbio.com\/products\/phospho-adducinalpha-t445-polyclonal-antibody-bt-phs00955","provider":"AFSBio Inc.","version":"1.0","type":"link"}