{"product_id":"phospho-ark-1-t288-polyclonal-antibody-bt-phs00645","title":"Phospho-ARK-1 (T288) Polyclonal Antibody - BT-PHS00645","description":"\u003cp\u003ePhospho-ARK-1 (T288) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00645-20, BT-PHS00645-50, BT-PHS00645-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by AURKA (aurora kinase A) is a cell cycle-regulated kinase that appears to be involved in microtubule formation and\/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for AURKA.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AURKA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-ARK-1 (T288) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 45809\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O14965; Mouse: P97477; Rat: P59241\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6; Aurora kinase A; Aurora 2; Aurora\/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine\/thre\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6790; Mouse: 20878\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240014405811,"sku":"BT-PHS00645-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240014438579,"sku":"BT-PHS00645-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240014471347,"sku":"BT-PHS00645-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c962d2b0-cd51-40fd-92c3-2a3889d7fce3.png?v=1769402144","url":"https:\/\/afsbio.com\/products\/phospho-ark-1-t288-polyclonal-antibody-bt-phs00645","provider":"AFSBio Inc.","version":"1.0","type":"link"}