{"product_id":"phospho-atf-2-t73-polyclonal-antibody-bt-phs00027","title":"Phospho-ATF-2 (T73) Polyclonal Antibody - BT-PHS00027","description":"\u003cp\u003ePhospho-ATF-2 (T73) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00027-20, BT-PHS00027-50, BT-PHS00027-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ATF2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IP, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-ATF-2 (T73) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 52277\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P15336; Mouse: P16951; Rat: Q00969\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CRE\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1386; Mouse: 1.00048e+008; Rat: 81647\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240005558451,"sku":"BT-PHS00027-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240005591219,"sku":"BT-PHS00027-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240005623987,"sku":"BT-PHS00027-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5aa19833-1404-4897-bd70-226ac027903a.png?v=1769402027","url":"https:\/\/afsbio.com\/products\/phospho-atf-2-t73-polyclonal-antibody-bt-phs00027","provider":"AFSBio Inc.","version":"1.0","type":"link"}