{"product_id":"phospho-atp-citrate-synthase-s455-polyclonal-antibody-bt-phs00686","title":"Phospho-ATP-citrate synthase (S455) Polyclonal Antibody - BT-PHS00686","description":"\u003cp\u003ePhospho-ATP-citrate synthase (S455) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00686-20, BT-PHS00686-50, BT-PHS00686-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACLY\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat, monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-ATP-citrate synthase (S455) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 120839\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P53396; Mouse: Q91V92; Rat: P16638\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 47; Mouse: 104112; Rat: 24159\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240014995635,"sku":"BT-PHS00686-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240015028403,"sku":"BT-PHS00686-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240015061171,"sku":"BT-PHS00686-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_749c841a-ca70-4bbb-8a2e-b3eec8cd3728.png?v=1769402154","url":"https:\/\/afsbio.com\/products\/phospho-atp-citrate-synthase-s455-polyclonal-antibody-bt-phs00686","provider":"AFSBio Inc.","version":"1.0","type":"link"}