{"product_id":"phospho-bcl-6-s333-polyclonal-antibody-bt-phs00460","title":"Phospho-Bcl-6 (S333) Polyclonal Antibody - BT-PHS00460","description":"\u003cp\u003ePhospho-Bcl-6 (S333) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00460-20, BT-PHS00460-50, BT-PHS00460-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by BCL6 (B-cell CLL\/lymphoma 6) is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. BCL6 is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for BCL6.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BCL6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-Bcl-6 (S333) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 78846\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P41182; Mouse: P41183\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 604; Mouse: 12053\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240011489459,"sku":"BT-PHS00460-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240011522227,"sku":"BT-PHS00460-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240011554995,"sku":"BT-PHS00460-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_90db5927-5c6b-492b-9651-bb8bb51391a4.png?v=1769402099","url":"https:\/\/afsbio.com\/products\/phospho-bcl-6-s333-polyclonal-antibody-bt-phs00460","provider":"AFSBio Inc.","version":"1.0","type":"link"}