{"product_id":"phospho-c3g-y504-polyclonal-antibody-bt-phs00377","title":"Phospho-C3G (Y504) Polyclonal Antibody - BT-PHS00377","description":"\u003cp\u003ePhospho-C3G (Y504) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00377-20, BT-PHS00377-50, BT-PHS00377-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RAPGEF1 encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RAPGEF1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-C3G (Y504) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 120548\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13905\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RAPGEF1; GRF2; Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2889\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240010211507,"sku":"BT-PHS00377-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240010244275,"sku":"BT-PHS00377-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240010277043,"sku":"BT-PHS00377-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_313774ea-52f2-400f-ab3e-e3b609a4f479.png?v=1769402083","url":"https:\/\/afsbio.com\/products\/phospho-c3g-y504-polyclonal-antibody-bt-phs00377","provider":"AFSBio Inc.","version":"1.0","type":"link"}