{"product_id":"phospho-cardiac-troponin-i-ser22-ser23-polyclonal-antibody-bz16417","title":"Phospho-Cardiac Troponin I (Ser22\/Ser23) Polyclonal Antibody-BZ16417","description":"\u003cp\u003ePhospho-Cardiac Troponin I (Ser22\/Ser23) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16417-50, BZ16417-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P23693\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 24 kDa; Observed MW: 28 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-Cardiac Troponin I in SH-SY5Y lysates using Phospho-Cardiac Troponin I antibody., EnzymeLinked Immunosorbent Assay for Immunogen Phospho-peptide and NonPhospho-peptide, using TNNI3 antibody., Immunohistochemistry analysis of paraffin-embedded Human skeletal muscle using TNNI3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right., Western blot analysis of Phospho-Cardiac Troponin I in mouse heart lysates using Phospho-Cardiac Troponin I antibody. The Lane on the right is blocked with the Phospho- peptide.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from rat TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43055904063667,"sku":"BZ16417-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43055904096435,"sku":"BZ16417-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f722497e-a732-4770-a1b7-3f7d7c474bbe.jpg?v=1708086399","url":"https:\/\/afsbio.com\/products\/phospho-cardiac-troponin-i-ser22-ser23-polyclonal-antibody-bz16417","provider":"AFSBio Inc.","version":"1.0","type":"link"}