{"product_id":"phospho-cd3-zeta-y142-polyclonal-antibody-bt-phs00051","title":"Phospho-CD3 Zeta (Y142) Polyclonal Antibody - BT-PHS00051","description":"\u003cp\u003ePhospho-CD3 Zeta (Y142) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS00051-20, BT-PHS00051-50, BT-PHS00051-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by CD247 (CD247 molecule) is T-cell receptor zeta, which together with T-cell receptor alpha\/beta and gamma\/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for CD247.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD247\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse, rat, monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-CD3 zeta (Y142) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 18696\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P20963; Mouse: P24161\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 919; Mouse: 12503\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240008507571,"sku":"BT-PHS00051-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240008540339,"sku":"BT-PHS00051-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240008573107,"sku":"BT-PHS00051-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5117af2c-180a-447b-9dd9-28165ff099f9.png?v=1769402057","url":"https:\/\/afsbio.com\/products\/phospho-cd3-zeta-y142-polyclonal-antibody-bt-phs00051","provider":"AFSBio Inc.","version":"1.0","type":"link"}