{"product_id":"phospho-cd4-s433-polyclonal-antibody-bt-phs01138","title":"Phospho-CD4 (S433) Polyclonal Antibody - BT-PHS01138","description":"\u003cp\u003ePhospho-CD4 (S433) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-PHS01138-20, BT-PHS01138-50, BT-PHS01138-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD4 (CD4 molecule) encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. CD4 is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology; Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD4\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospho-CD4 (S433) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 51111\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P01730; Mouse: P06332\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4\/Leu-3; CD antigen CD4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 920; Mouse: 12504\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240023154867,"sku":"BT-PHS01138-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240023187635,"sku":"BT-PHS01138-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240023220403,"sku":"BT-PHS01138-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d91d691e-69df-4dee-91fe-c4235ab8fec6.png?v=1769402284","url":"https:\/\/afsbio.com\/products\/phospho-cd4-s433-polyclonal-antibody-bt-phs01138","provider":"AFSBio Inc.","version":"1.0","type":"link"}