{"product_id":"phospho-doublecortin-ser297-recombinant-rabbit-monoclonal-antibody-bs43269","title":"Phospho-Doublecortin (Ser297) Recombinant Rabbit Monoclonal Antibody - BS43269","description":"\u003cp\u003ePhospho-Doublecortin (Ser297) Recombinant Rabbit mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS43269-50, BS43269-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubμles. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regμlating the organization and stability of microtubμles. In addition, the encoded protein interacts with LIS1, the regμlatory gamma subunit of platelet activating factor acetylhydrolase. Studies in knockout mice lacking this gene and the LIS1 gene suggest that the molecμlar interaction of these two genes is important in both in neuronal migration and neurogenesis, and there is a cortical role of this gene in nuclear translocation and positioning of the mitotic spindle in radial glial mitotic division. Mμltiple transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IP\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Dbct\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic phosphopeptide corresponding to residues surrounding \u003cbr\u003e\nSer297 of mouse Doublecortin\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:1000 IHC: 1:20-1:500 IP: 1:20\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 41 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: O88809\u003c\/p\u003e\n\n\u003cp\u003eProduct: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45937124311219,"sku":"BS43269-50","price":424.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45937124343987,"sku":"BS43269-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/phospho-doublecortin-ser297-recombinant-rabbit-monoclonal-antibody-bs43269","provider":"AFSBio Inc.","version":"1.0","type":"link"}