{"product_id":"phospho-erk1-2-tyr222-tyr205-10c8-monoclonal-antibody-mb3298","title":"Phospho-ERK1\/2 (Tyr222\/Tyr205) (10C8) Monoclonal Antibody-MB3298","description":"\u003cp\u003ePhospho-ERK1\/2 (Tyr222\/Tyr205) (10C8) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3298-50, MB3298-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P27361\/P28482\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC: 1\/50-1\/100\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Serine\/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1\/ERK2 and MAPK3\/ERK1 are the 2 MAPKs which play an important role in the MAPK\/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG\/SCF. Depending on the cellular context, the MAPK\/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: -\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1\/2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using Phospho-ERK1\/2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: MAPK1\/MAPK3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide conjugated to KLH.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970468614323,"sku":"MB3298-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970468647091,"sku":"MB3298-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fa9e1325-429c-4c2f-9d05-4c080b40d25b.jpg?v=1705525744","url":"https:\/\/afsbio.com\/products\/phospho-erk1-2-tyr222-tyr205-10c8-monoclonal-antibody-mb3298","provider":"AFSBio Inc.","version":"1.0","type":"link"}