{"product_id":"phospho-estrogen-receptor-alpha-ser118-polyclonal-antibody-bz16290","title":"Phospho-Estrogen Receptor alpha (Ser118) Polyclonal Antibody-BZ16290","description":"\u003cp\u003ePhospho-Estrogen Receptor alpha (Ser118) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16290-50, BZ16290-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P03372\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  ICC: 1\/100-1\/200\u003c\/p\u003e\n\n\u003cp\u003eBackground: ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 66 kDa; Observed MW: 66 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-Estrogen Receptor alpha in MDAMB435 lysates using Phospho-Estrogen Receptor alpha antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Estrogen Receptora antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-Estrogen Receptor alpha in MCF-7 cells using Estrogen Receptora antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human ESR1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42999932158131,"sku":"BZ16290-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42999932190899,"sku":"BZ16290-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_445611ac-e1ed-403d-b856-8538b482b9e4.jpg?v=1706358286","url":"https:\/\/afsbio.com\/products\/phospho-estrogen-receptor-alpha-ser118-polyclonal-antibody-bz16290","provider":"AFSBio Inc.","version":"1.0","type":"link"}