{"product_id":"phospho-glucocorticoid-receptor-ser211-polyclonal-antibody-e-ab-21144","title":"Phospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody - E-AB-21144","description":"\u003cp\u003ePhospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-21144-60, E-AB-21144-120, E-AB-21144-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GR (phospho Ser211)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GCCR; GCR; GCR; GCRST; glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor; GR; GRL; Grl1; nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3; group C; member 1 (glucocorticoid receptor)\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P04150\u003c\/p\u003e\n\n\u003cp\u003eBackground: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human GR around the phosphorylation site of  Ser211\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 86kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 95kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146003873971,"sku":"E-AB-21144-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146003906739,"sku":"E-AB-21144-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146003939507,"sku":"E-AB-21144-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_fb551baf-4e84-4224-9c87-18a5abef35b5.png?v=1710289618","url":"https:\/\/afsbio.com\/products\/phospho-glucocorticoid-receptor-ser211-polyclonal-antibody-e-ab-21144","provider":"AFSBio Inc.","version":"1.0","type":"link"}