{"product_id":"phospho-gsk3-tyr279-tyr216-polyclonal-antibody-bz16306","title":"Phospho-GSK3 (Tyr279\/Tyr216) Polyclonal Antibody-BZ16306","description":"\u003cp\u003ePhospho-GSK3 (Tyr279\/Tyr216) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16306-50, BZ16306-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49840\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  ICC: 1\/100-1\/200\u003c\/p\u003e\n\n\u003cp\u003eBackground: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 51 kDa; Observed MW: 46,51 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-GSK3 in 293 lysates using Phospho-GSK3 alpha\/beta antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-GSK3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-GSK3 in Hela cells using GSK3a\/b antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Serine\/threonine-protein kinase GSK3A\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide of human GSK3A\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42999932584115,"sku":"BZ16306-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42999932616883,"sku":"BZ16306-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ef22726e-4b9f-4c63-8fc6-09e276080c70.jpg?v=1706358303","url":"https:\/\/afsbio.com\/products\/phospho-gsk3-tyr279-tyr216-polyclonal-antibody-bz16306","provider":"AFSBio Inc.","version":"1.0","type":"link"}