{"product_id":"phospho-hdac6-ser22-polyclonal-antibody-e-ab-21286","title":"Phospho-HDAC6 (Ser22) Polyclonal Antibody - E-AB-21286","description":"\u003cp\u003ePhospho-HDAC6 (Ser22) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-21286-60, E-AB-21286-120, E-AB-21286-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HDAC6 (phospho Ser22)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CPBHM; FLJ16239; HD 6; HD6; HDAC 6; HDAC6; HDAC6; Histone deacetylase 6 (HD6); Histone deacetylase 6; JM 21; JM21; KIAA0901; OTTHUMP00000032398; OTTHUMP00000197663; PPP1R90; Protein phosphatase 1 regulatory subunit 90\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UBN7\u003c\/p\u003e\n\n\u003cp\u003eBackground: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human HDAC6 around the phosphorylation site of  Ser22\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 131kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 131kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146004463795,"sku":"E-AB-21286-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146004496563,"sku":"E-AB-21286-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146004529331,"sku":"E-AB-21286-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2bcd25bf-37ba-4461-b079-69389578c102.png?v=1710289634","url":"https:\/\/afsbio.com\/products\/phospho-hdac6-ser22-polyclonal-antibody-e-ab-21286","provider":"AFSBio Inc.","version":"1.0","type":"link"}