{"product_id":"phospho-histone-h2a-x-ser139-monoclonal-antibody-mb10958","title":"Phospho-Histone H2A.X (Ser139) Monoclonal Antibody-MB10958","description":"\u003cp\u003ePhospho-Histone H2A.X (Ser139) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10958-50, MB10958-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P16104\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 15 kDa; Observed MW: 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of gamma H2A. X in HepG2 lysates using Phospho-Histone H2A. X antibody., Western blot analysis of gamma H2A. X in Jurkat, THP-1, C6, 3T3 lysates using gamma H2A. X antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: H2A.X; H2AFX; H2a\/x; HIST5-2AX; Histone H2A.X; gamma H2A.X\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970497876147,"sku":"MB10958-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970497908915,"sku":"MB10958-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_792977ef-f31d-4cee-a571-91bd06f75b4b.jpg?v=1705526444","url":"https:\/\/afsbio.com\/products\/phospho-histone-h2a-x-ser139-monoclonal-antibody-mb10958","provider":"AFSBio Inc.","version":"1.0","type":"link"}