{"product_id":"phospho-igf1-receptor-tyr1165-tyr1166-polyclonal-antibody-bz16111","title":"Phospho-IGF1 Receptor (Tyr1165\/Tyr1166) Polyclonal Antibody-BZ16111","description":"\u003cp\u003ePhospho-IGF1 Receptor (Tyr1165\/Tyr1166) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16111-50, BZ16111-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P08069\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 155 kDa; Observed MW: 155 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-IGF1 Receptor in various lysates using Phospho-IGF1 Receptor antibody., Western blot analysis of Phospho-IGF1 Receptor in COS7 lysates using Phospho-IGF1 Receptor antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165\/Tyr1166. AA range:1131-1180\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970471202995,"sku":"BZ16111-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970471235763,"sku":"BZ16111-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_02e42909-583c-4b96-ae43-b08d084d8a80.jpg?v=1705525806","url":"https:\/\/afsbio.com\/products\/phospho-igf1-receptor-tyr1165-tyr1166-polyclonal-antibody-bz16111","provider":"AFSBio Inc.","version":"1.0","type":"link"}