{"product_id":"phospho-jak2-3-tyr966-939-polyclonal-antibody-bz16115","title":"Phospho-JAK2\/3 (Tyr966\/939) Polyclonal Antibody-BZ16115","description":"\u003cp\u003ePhospho-JAK2\/3 (Tyr966\/939) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16115-50, BZ16115-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O60674\/P52333\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 131 kDa; Observed MW: 120-130 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-JAK2\/3 in mouse liver, hela , mouse brain lysates using Phospho-JAK2\/3 antibody., Western blot analysis of Phospho-JAK2\/3 in hela lysates using Phospho-JAK2\/3 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Tyrosine-protein kinase JAK2\/JAK3 (EC 2.7.10.2; Janus kinase 2\/Janus kinase 3; JAK-2\/JAK-3)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized Phospho peptide derived from human JAK2\/3.at AA range: T966\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970471465139,"sku":"BZ16115-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970471497907,"sku":"BZ16115-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_483f10d9-49c0-40ee-aed3-6c80bc53542e.jpg?v=1705525817","url":"https:\/\/afsbio.com\/products\/phospho-jak2-3-tyr966-939-polyclonal-antibody-bz16115","provider":"AFSBio Inc.","version":"1.0","type":"link"}