{"product_id":"phospho-kappa-opioid-receptor-ser369-polyclonal-antibody-bz16413","title":"Phospho-kappa Opioid Receptor (Ser369) Polyclonal Antibody-BZ16413","description":"\u003cp\u003ePhospho-kappa Opioid Receptor (Ser369) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16413-50, BZ16413-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P41145\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 43 kDa; Observed MW: 43 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-kappa Opioid Receptor in various lysates using Phospho-kappa Opioid Receptor antibody., Western blot analysis of Phospho-kappa Opioid Receptor in rat kidney lysates using Phospho-KOR1 antibody., Immunohistochemistry analysis of paraffin-embedded Human brain using Phospho-kappa Opioid Receptor antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.Sample with blocking peptide on the right., Western blot analysis of Phospho-kappa Opioid Receptor in NIH\/3T3 lysates using Phospho-kappa Opioid Receptor antibody. The Lane on the right is blocked with the Phospho- peptide.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from KOR-1 around the phosphorylation site of Ser369. AA range:331-380\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43055903867059,"sku":"BZ16413-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43055903899827,"sku":"BZ16413-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4ba7be29-9f09-4445-bf61-2bc62465abd1.jpg?v=1708086394","url":"https:\/\/afsbio.com\/products\/phospho-kappa-opioid-receptor-ser369-polyclonal-antibody-bz16413","provider":"AFSBio Inc.","version":"1.0","type":"link"}